Dysfunction in the human immune system plays a central role in a wide variety of diseases. It can be a defining feature in diseases such as cancer and autoimmune disorders like inflammatory bowel disease, multiple sclerosis, and rheumatoid arthritis. It is also being uncovered in diseases ranging from neurodegenerative and neuropsychiatric disorders to heart diseases.

The Broad’s Immunology Program brings a multi-disciplinary lens to deciphering the immune processes that play a central role in both healthy and disease states. By bringing together faculty with varied backgrounds, it hopes to advance our knowledge of specific immune cells, to characterize how these cells participate in their immediate environment within the organ, and to understand how these cells interact with other cells as well as pathogens. Our investigators are working to draw an unprecedented map for immune function and thus lay the groundwork for potential therapeutic interventions.

We are seeking philanthropic partners in the following projects:

  • Discovering and fully defining the biological mechanisms underlying autoimmune and inflammatory diseases.

  • Developing ways to predict these diseases.

  • Developing powerful new tools to characterize and exploit immune function, and drive the discovery and testing of novel therapeutics for autoimmune, inflammatory, and infectious diseases.

News coverage on our research in immunology