Mission The Broad Institute of MIT and Harvard is an independent research institution dedicated to accelerating the pace at which the world conquers disease. Our Mission Read about the Broad Mission Priorities The Broad Institute pursues high-impact projects focused on major human diseases. Donor Impact Private philanthropy has played a critical role at the Broad Institute from the very beginning. VIDEO: Rare Cancer Dependency Map Initiative Watch how a new collaborative effort at the Broad is accelerating research into rare cancers. Targeting Cancer’s Achilles Heel MCL1 is one of the most common culprits in cancer. Broad researchers recently identified a small molecule that appears to inhibit the gene’s activity. Beating Back Cancer Drug Resistance Drug resistance has confounded cancer researchers since the 1940s. For the first time, we have the power to understand the details of how it works.