Mission The Broad Institute of MIT and Harvard is an independent research institution dedicated to accelerating the pace at which the world conquers disease. Our Mission Read about the Broad Mission Priorities The Broad Institute pursues high-impact projects focused on major human diseases. Donor Impact Private philanthropy has played a critical role at the Broad Institute from the very beginning. A Helpful Handbook to the Human Genome How can we learn which mutations are harmless, and which ones cause devastating disease? Fixing Friedreich’s Ataxia The Broad partners with a patient’s family to unravel—and cure—a rare neurological disorder. Video: A Collaborative Scientific Community The Broad Institute brings passionate, multi-disciplinary researchers under one roof to solve some of biomedicine's biggest challenges.