Meet Our Researchers

Miguel Reyes

Graduate Researcher, Broad Institute
Biological Engineering Ph.D. Student, Massachusetts Institute of Technology

Miguel Reyes is searching for clues as to why Covid-19 hits some patients much harder than others by examining its similarities to sepsis.

Project Description

Severe Covid-19 and sepsis share similar symptoms—multi-organ failure, shortness of breath, fever, confusion—and both are associated with dysregulated immune response. Miguel and his team recently discovered another connection: The blood cells of patients with severe forms of these diseases have different baseline gene expression profiles than those with mild infection. With BroadIgnite support, Miguel wants to expand this work to identify which immune response pathways are altered in these patients—and whether they can be harnessed as new treatment avenues.