Genome-wide association studies have linked genetic variants to specific phenotypes and disease risks, but we still do not fully grasp how these variants impact biological processes, or have the tools to identify variants that may emerge in the future. With his BroadIgnite project, Konrad plans to address this gap by analyzing the genetics of healthy individuals to detail the landscape of genetic variants—both common and rare—and link them to biological functions. Importantly, he will also build tools to predict new variants, including those that do not exist within the population yet as well as ones that have not been identified in studies so far.